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KMID : 0882420040670030297
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Korean Journal of Medicine
2004 Volume.67 No. 3 p.297 ~ p.301
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A case of latex fruit syndrome caused by spinach and eggplant
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Lee Jae-Chun
Cho You-Sook
Kim Youn-Yee
Koh Su-Jin
Lee Tae-Hoon
Moon Hee-Bom
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Abstract
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Spinach (Spinacia oleracea) is a widely consumed vegetable, but rarely causes allergic reactions. Spinach contains plenty of histamine derivatives, so it is sometimes difficult to distinguish food allergy from pharmacologic effect of histamine itself in susceptible individuals. Latex exhibits strong cross reactivity with proteins from different fruits, vegetables, and grains, which is called as latex fruit syndrome. A 27 year old female visited emergency room with hives, facial swelling, dyspnea and palpitation immediately after meal. She had been suffering from latex allergy and had experienced an episode of anaphylaxis after eating eggplant 5 months earlier. Skin prick test with spinach extract was positive. Specific IgE to spinach antigens was detected by ELISA. ELISA inhibition test revealed that there is cross reactivity between latex and spinach. Two IgE binding components were detected between 22kD and 36kD, and another two between 16kD and 22kD on IgE-immunoblot analysis.
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KEYWORD
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Anaphylaxis, Eaaplant, Food allergy, Latex fruit syndrome, Spinach
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